Proteins: Structure-function Relationships
Medical Biology
Institute of Health Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Proteins: Structure-function Relationships | TBG614 | Elective | Doctorate degree | 1 | Spring | 6 |
Name of Lecturer(s)
Prof. Dr. Gürler AKPINAR
Prof. Dr. Murat KASAP
Learning Outcomes of the Course Unit
1) Learn about the physical and chamical properties of amino acids, learn about primer, seconder, tertiar and quaterner structures of proteins, predict how proteins fold into thier 3D structures, determine active sites of proteins
Program Competencies-Learning Outcomes Relation
| Program Competencies | ||||||||||||||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | ||
| Learning Outcomes | ||||||||||||||||
| 1 | Low | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Biochemistry
Course Contents
Aminoacids and primary structure of proteins, Peptide bond formation, sekondary structure of proteins, Tertiary structure of proteins, quaternary structure of proteins, Overall 3D structure of proteins, how to determine active sites of proteins.
Weekly Schedule
1) Amino acids2) Protein structure
3) Purification of proteins and characteristics of proteins
4) Protein sequencing
5) Enzymes
6) Enzyme kinetics
7) Hemoglobin and cooperative binding
8) Midterm exam
9) Immunoproteins
10) Motor proteins and movement
11) Transport proteins
12) Intracellular protein transport-1
13) Intracellular protein transport-2
14) Chaperone proteins
15) Revision time
16) Final exam
Recommended or Required Reading
1- Structure Function Relationship in Proteins. David Whitford
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
4) Problem Solving
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
40% |
|---|---|
Contribution of Final Examination to Course Grade |
60% |
Total |
100% |
Language of Instruction
Turkish
Work Placement(s)
Not Required